El PRFC-PRP, Plasma Rico en Factores de Crecimiento, es una técnica de regeneración de tejidos óseos y tisulares. Fibrina autologa, bioestimulacion cutanea. PRAS agentes señalizadores. Plaquetas, autoinjerto. Cirugia    

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Congreso Internacional de Medicina Antienvejecimiento


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Proteal. El PRFC-PRP, Plasma Rico en Factores de Crecimiento (Platelet Rich Plasma - Growth Factors), es una técnica de regeneración de tejidos óseos y tisulares. Fibrina autologa, bioestimulacion cutanea. PRAS agentes señalizadores. Plaquetas, autoinjerto. Cirugia
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Neurología
  1. Stover, E.P., et al, Intraoperatively Prepared Platelet Gel as an Alternative to Fibrin Glue in Dural Wound Repair, Transfusion, 1996; 36:46S.
  2. Hood, et al, Preoperative Autologous Sequestration III: A new Physiologic Glue with Wound Healing Properties, Proceedings of the American Academy of Cardiovascular Perfusion, 1993;14:126.


Cirugía plástica y reconstrucctiva
  1. Man, Daniel, Posker Harvey, Winland-Brown, Jill E., The Use of Autologous Platelet-Rich Plasma (Platelet Gel) and Autologous Platelet-Poor Plasma (Fibrin Glue) in Cosmetic Surgery, Plastic and Reconstructive Surgery, 2001; 229-239.
  2. NewsEdge, Modulation of tissue In-growth Into Porous High-Density Polyethylene Implants With Basic Fibroblast Growth Factor and Autologous Blood Clot, Arch Facial Plast Surg. 2000;2:27-33.
  3. Green, D.M., Platelet Gel as an Intraoperatively Procured Platelet-Based Alternative to Fibrin Glue, Plastic and Reconstructive Surgery, 1998; 101:1161-1162.
  4. Man, D., A South Florida Plastic Surgeon, Increases Wound Healing Through Innovative Surgical Procedure Patient's Blood Used to Produce Gel That Increases Wound Healing and Decreases, HeadsUp, June, 1999.
  5. Welsh, William J., Platelet Gel Usage in Cosmetic Surgery, American Academy of Cosmetic Surgery, January 27, 2000.
  6. Lorenz, H. Peter, et al, The Impact of Biomolecular Medicine and Tissue Engineering on Plastic Surgery in the 21st Century, Plastic and Reconstructive Surgery, 2000; 2467-2481.
  7. Kron, Joan, Everything you always wanted to know about plastic surgery but were afraid to ask, Allure, 2000; 174-179:199-200.
  8. Tram Flap Breast reconstruction with Expanders and implants, AORN Journal, 2000;VOL. 71.
  9. Welsh, William J., Autologous Platelet Gel- Clinical Function and Usage in Plastic Surgery, Cosmetic Dermatology, July 2000; 13-18.
  10. Adler, Stephen C., Autologous Platelet Gel in Facial Plastic Surgery; 2000; 1-8.


Úlceras y Heridas no cicatrizantes
  1. Pierce, G. F., et al, Platelet-Derived Growth Factor-BB and Transforming Growth Factor Beta 1 Selectively Modulate Glycosaminoglycans, Collagen, and Myofibroblasts in Excisional Wounds, American Journal of Pathologists, 1991; 138:629-646.
  2. Robson, M., et al, Recombinant Human Platelet-derived Growth Factor-BB for the Treatment of Chronic Pressure Ulcers, Annals of Plastic Surgery, 1992; 29:193-201.
  3. Pierce, et al, Role of Platelet Derived Growth Factor in Wound Healing, Journal Cellular Biochemistry, 1991; 45:319-326.
  4. Pierce, et al, Detection of Platelet Derived Growth Factor (PDGF-AA) in Actively Healing Human Wounds Treated with Recombinant PDGF-BB and absence of GDGF in healing wounds, Journal Clinical Investigation, 1995; 96:1336-50.
  5. Knighton, D.R., et al, Role of Platelets and Fibrin in the Healing Sequence, Annals of Surgery, 1982; 196;379-388.
  6. Folkman, J., Is There a Field of Wound Pharmacology?, Annals of Surgery, 1992; 244:1-2.
  7. Ksander, G. A., et al, The Effect of Platelet Release on Wound Healing in Animal Models, Journal of American Academy of Dermatology, 1990; 22:781-791.
  8. Knighton, D.R., et al, Stimulation of Repair in Chronic, Nonhealing, Cutaneous Ulcers Using Platelet-Derived Wound Healing Formula, Surgery, Gynecology & Obstetrics, 1990; 170; 56-60.
  9. Knighton, D.R., et al, Classification and Treatment of Chronic Nonhealing Wounds: Successful Treatment with Autologous Platelet-Derived Wound Healing Factors (PDWHF), Annals of Surgery, 1986; 204:322-330.
  10. Steed, et al, Clinical Evaluation of Recombinant Human Platelet-Derived Growth Factor for the Treatment of Lower Extremity Diabetic Ulcers, Diabetic Ulcer Study Group, Journal Vascular Surgery, 1995; 21(1):71-8; discussion 79-81.
  11. Krupski, William C., et al, A Prospective Randomized Trial of Autologous Platelet-Derived Wound Healing Factors for Treatment of Chronic Nonhealing Wounds: A Preliminary Report, Journal of Vascular Surgery, 1991; 14:526-536.
  12. Wieman, T.J., et al, Efficacy and Safety of a Topical Gel Formulation of Recombinant Human Platelet-Derived Growth Factor-BB (Becaplermin) in Patients with Chronic Neupropathic Diabetic Ulcers, Diabetes Care, 1998; 21:822-827.


Adhesivo de Fibrina
  1. Oz, M.C., et al, Autologous Fibrin Glue From Intraoperatively Collected Platelet-Rich Plasma, Annals of Thoracic Surgery, 1992; 53:530-531.
  2. Gibble, J.W., et al, Fibrin Glue: The Perfect Operative Sealant?, Transfusion, 1990; 30:741-747.
  3. Hartman, A. R., et al, Autologous Whole Plasma Fibrin Gel - Intraoperative Procurement, Arch Surgery, 1992; 127:357-359.
  4. Radosevich, M., et al, Fibrin Sealant: Scientific Rationale, Production Methods, Properties, and Current Clinical Use, Vox Sang, 1997; 72:133-134.
  5. Dhall, T.Z., et al, Fibrin Network Structure: Modification by Platelets, Thromb Haemostas, 1983; 49:42-46.
  6. Dulchavsky, Scott A, et al, Autologous Fibrin Gel: Bactericidal Properties in Contaminated Hepatic Injury, The Journal of Trauma, 1991; 31:991-994
  7. McGill, Victoria, et al, Use of Fibrin Sealant in Thermal Injury, Journal of Burn Care & Rehabilitation, 1997; 18:429-434.
  8. Byrne, D.J., et al, Effect of Fibrin Glues on the Mechanical Properties of Healing Wounds, British Journal of Surgery, 1991; 78:841-843.
  9. Blackstone, Michael O., Fibrin Glue for Bleeding Peptic Ulcers, The Lancet, 1997; 350:679.
  10. Kram, Harry B., Fibrin Glue Achieves Hemostasis in Patients with Coagulation Disorders, Arch Surgery, 1989; 124:385-387.
  11. Holcomb, John B., et al, Implications of New Dry Fibrin Sealant Technology for Trauma Surgery, Surgical Clinics of North America, 1997; 77:943-952.
  12. NewsEdge, Repair of Chronic Anorectal Fistulae Using Commercial Fibrin Sealant, Arch Surg. 2000;135:166-169
  13. Cintron, Jose R., Commercial Fibrin Sealant Safe and Effective Treatment for Anorectal Fistulae, Arch Surg. 2000; 135:166-169.
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